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Antigenic Specificity | Human CD1d |
Clone | D5 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | Protein A/G purified, low endotoxin |
Size | 50mg |
Concentration | ≥ 5.0 mg/ml |
Applications | Immunoprecipitation, Western Blot. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Clone D5 recognizes an epitope on human CD1d. CD1d antibody, D5, recognizes human CD1d, also known as CD1.1 and Ly-38, a 48 kDa type 1 membrane glycoprotein that belongs to the cluster of differentiation 1 (CD1) family of glycoproteins. CD1d is expressed on epithelial cells and monocyte-derived antigen presenting cells (APCs), including monocytes, DCs, and macrophages. CD1d is an MHC class I-like molecule involved in the presentation of lipid antigens, such as α-galactosylceramide (α-GalCer), to a highly conserved T cell subset, named invariant natural killer T (iNKT) cells or CD1d-restricted T cells1. Following activation, iNKT cells rapidly proliferate and produce large amounts of cytokines and cytolytic mediators |
Immunogen | CD1d a1-a2 domains |
Other Names | R3G1 |
Gene, Accession # | UniProt: P15813 |
Catalog # | ICH1177UL-50mg |
Price | $2300 |
Order / More Info | Human CD1d Antibody from ICHORBIO |
Product Specific References | n/a |
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