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Antigenic Specificity | CD161, Rat |
Clone | REA227 |
Host Species | Recombinant Human |
Reactive Species | rat |
Isotype | IgG1 |
Format | fluorescein (FITC) conjugate |
Size | 30 µg in 1 mL |
Concentration | 1:10 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD161 Antibody, anti-rat, FITC, REAfinity™. Clone REA227 recognizes rat CD161, a C-type lectin membrane glycoprotein also known as NKR-P1. CD161 is expressed as an 80 kDa disulphide-linked homodimer and is found on most NK cells, T cell subsets, and many dendritic cells. In peripheral blood, CD161 is preferentially expressed on T cells of memory phenotype, but it can also be found on subsets of thymocytes and fetal liver T cells. CD161 has been implicated in triggering NK-mediated cytotoxicity, contributing to target cell recognition by NK cells. | Additional information: Clone REA227 displays negligible binding to Fc receptors. | |
Immunogen | n/a |
Other Names | NK1.1, NKR-P1C, Ly-55 |
Gene, Accession # | Gene ID: 25192, 362443, 678513, 689817, 683758 |
Catalog # | 130-102-711 |
Price | $48 |
Order / More Info | CD161, Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Giorda, R. et al. (1990) NKR-P1, a signal transduction molecule on natural killer cells. Science 249 (4974): 1298-1300. | Li, J. et al. (2003) Expression cloning and function of the rat NK activating and inhibitory receptors NKR-P1A and -P1B. Int. Immunol. 15 (3): 411-416. |