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Antigenic Specificity | IL1A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of various cell lines, using IL1A antibody. Immunohistochemical of paraffin-embedded human lung cancer using IL1A antibody at dilution of 1:200 (400x lens). IL-1+/- is a pro-inflammatory cytokine produced by activated monocytes, lymphocytes and epithelial cells (1). IL-1+/- is synthesized as an active precursor protein that appears to be cleaved by cytosolic proteases into its mature form (1, 2). Often, precursor and mature forms of IL-1+/- are primarily retained intracellularly rather than constitutively secreted. (1, 2). Signaling by IL-1+/- involves IL-1+/- binding to an IL-1 accessory protein (IL-1-AcP) and then the complex binds to IL-1RI (1, 2). Signaling is through activation of MAP kina |
Immunogen | Immunogen: Recombinant protein of human IL1A |
Other Names | [interleukin-1 alpha; Interleukin-1 alpha; interleukin-1 alpha; interleukin 1 alpha; Hematopoietin-1] |
Gene, Accession # | [IL1A], Gene ID: 3552, NCBI: NP_000566.3, UniProt: P01583 |
Catalog # | MBS4150025 |
Price | $385 |
Order / More Info | IL1A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |