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Antigenic Specificity | CD44 (C-term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CD44 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 688-722 amino acids from the C-terminal region of human CD44. Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogene |
Immunogen | n/a |
Other Names | [CD44 antigen; CDw44; Epican; Extracellular matrix receptor III; ECMR-III; GP90 lymphocyte homing/adhesion receptor; HUTCH-I; Heparan sulfate proteoglycan; Hermes antigen; Hyaluronate receptor; Phagocytic glycoprotein 1; PGP-1; Phagocytic glycoprotein I; PGP-I; CD44; CD44; LHR; MDU2; MDU3; MIC4] |
Gene, Accession # | [CD44], Gene ID: 960, NCBI: NP_000601.3, UniProt: P16070 |
Catalog # | MBS9207166 |
Price | $165, $370 |
Order / More Info | CD44 (C-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Stamenkovic I.,et al.Cell 56:1057-1062(1989). Harn H.-J.,et al.Biochem. Biophys. Res. Commun. 178:1127-1134(1991). Stamenkovic I.,et al.EMBO J. 10:343-348(1991). Dougherty G.J.,et al.J. Exp. Med. 174:1-5(1991). Kugelman L.C.,et al.J. Invest. Dermatol. 99:886-891(1992). |