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Antigenic Specificity | Human Ubiquitin-conjugating enzyme E2 K |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, in the presence or in the absence of BRCA1-BARD1 E3 ubiquitin-protein ligase complex, catalyzes the synthesis of 'Lys-48'-linked polyubiquitin chains. Does not transfer ubiquitin directly to but elongates monoubiquitinated substrate protein. Mediates the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins. Ubiquitinates huntingtin. May mediate foam cell formation by the suppression of apoptosis of lipid-bearing macrophages through ubiquitination and subsequence degradation of p53/TP53. Proposed to be involved in ubiquitination and proteo |
Immunogen | Immunogen: Recombinant human Ubiquitin-conjugating enzyme E2 K protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-50733 / sc-50736 |
Other Names | [Huntingtin-interacting protein 2; Ubiquitin carrier protein; Ubiquitin-conjugating enzyme E2-25 kDa; Ubiquitin-protein ligase; HIP2; LIG], [UBE2K; UBE2K; LIG; HIP2; HYPG; UBC1; E2-25K; HIP2; LIG; HIP-2; Ubiquitin-conjugating enzyme E2(25K); Ubiquitin-conjugating enzyme E2-25K] |
Gene, Accession # | [UBE2K], Gene ID: 3093, NCBI: NP_001104582.1, UniProt: P61086 |
Catalog # | MBS1488474 |
Price | $160, $235 |
Order / More Info | Human Ubiquitin-conjugating enzyme E2 K Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |