Edit |   |
---|---|
Antigenic Specificity | FBXL14 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, bovine, rabbit, dog, chicken, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: FBXL14 Antibody detects endogenous levels of FBXL14. Description: Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin-protein ligase complexes. The SCF(FBXL14) complex acts by mediating ubiquitination and subsequent degradation of SNAI1.Subunit Structure: Part of a SCF (SKP1-cullin-F-box) ubiquitin-protein ligase complex. Interacts with SKP1 and CUL1 (By similarity). Interacts with SNAI1; the interaction requires the phosphorylation of the two serine residues in the substrate destruction motif D-S-G-X(2,3,4)-S. |
Immunogen | Immunogen: A synthesized peptide derived from human FBXL14. Tissue Specificity: Down-regulated by hypoxia. |
Other Names | [F-box/LRR-repeat protein 14; F-box/LRR-repeat protein 14; F-box/LRR-repeat protein 14; F-box and leucine rich repeat protein 14; F-box and leucine-rich repeat protein 14] |
Gene, Accession # | [FBXL14], Gene ID: 144699, NCBI: NP_689654.1, UniProt: Q8N1E6 |
Catalog # | MBS9611756 |
Price | $240, $280 |
Order / More Info | FBXL14 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |