Human F-box/WD repeat-containing protein 11 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman F-box/WD repeat-containing protein 11
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.05 mL, 0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Immunohistochemistry (IHC)
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DescriptionSubstrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. SCF(FBXW11) mediates the ubiquitination of phosphorylated CTNNB1 and participates in Wnt signaling. SCF(FBXW11) mediates the ubiquitination of phosphorylated NFKBIA, which degradation frees the associated NFKB1 to translocate into the nucleus and to activate transcription. SCF(FBXW11) mediates the ubiquitination of IFNAR1. Involved in the oxidative stress-induced a ubiquitin-mediated decrease in RCAN1. Mediates the degradation of CDC25A induced by ionizing radiation in cells progressi
ImmunogenImmunogen: Recombinant human F-box/WD repeat-containing protein 11 protein (1-140aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-9599
Other Names[F-box and WD repeats protein beta-TrCP2; F-box/WD repeat-containing protein 1B; Homologous to Slimb protein; HOS; FBXW11; BTRCP2; FBW1B; FBXW1B; KIAA0696], [FBXW11; FBXW11; Hos; BTRC2; FBW1B; Fbw11; BTRCP2; FBXW1B; BTRCP2; FBW1B; FBXW1B; KIAA0696; HOS]
Gene, Accession #[FBXW11], Gene ID: 23291, NCBI: NP_036432.2, UniProt: Q9UKB1
Catalog #MBS1499789
Price$120, $160
Order / More InfoHuman F-box/WD repeat-containing protein 11 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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