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Antigenic Specificity | Human F-box/WD repeat-containing protein 11 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. SCF(FBXW11) mediates the ubiquitination of phosphorylated CTNNB1 and participates in Wnt signaling. SCF(FBXW11) mediates the ubiquitination of phosphorylated NFKBIA, which degradation frees the associated NFKB1 to translocate into the nucleus and to activate transcription. SCF(FBXW11) mediates the ubiquitination of IFNAR1. Involved in the oxidative stress-induced a ubiquitin-mediated decrease in RCAN1. Mediates the degradation of CDC25A induced by ionizing radiation in cells progressi |
Immunogen | Immunogen: Recombinant human F-box/WD repeat-containing protein 11 protein (1-140aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-9599 |
Other Names | [F-box and WD repeats protein beta-TrCP2; F-box/WD repeat-containing protein 1B; Homologous to Slimb protein; HOS; FBXW11; BTRCP2; FBW1B; FBXW1B; KIAA0696], [FBXW11; FBXW11; Hos; BTRC2; FBW1B; Fbw11; BTRCP2; FBXW1B; BTRCP2; FBW1B; FBXW1B; KIAA0696; HOS] |
Gene, Accession # | [FBXW11], Gene ID: 23291, NCBI: NP_036432.2, UniProt: Q9UKB1 |
Catalog # | MBS1499789 |
Price | $120, $160 |
Order / More Info | Human F-box/WD repeat-containing protein 11 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |