SKP2/p45 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-SKP2/p45 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | SKP2/p45 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: SKP2/p45 antibody detects endogenous levels of SKP2/p45. Description: SKP2 an F-box protein of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase system. The F-box component of the SCF complex is responsible for recognizing different substrates for ubiquitination. The SCF E3 complex mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition. Degradation of CDKN1B/p27kip also requires CKS1. Three alternatively-spliced isoforms have been described.Function: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) |
| Immunogen | Immunogen: A synthesized peptide derived from human SKP2/p45 Subcellular Location: Nucleus Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken Similarity: Pig (100%), Bovine (100%), Horse (90%), Sheep (100%), Rabbit (100%), Dog (90%), Chicken (80%) |
| Other Names | [CDK2/Cyclin A associated protein p45; Cyclin A/CDK2 associated protein p45; Cyclin-A/CDK2-associated protein p45; F box protein Skp2; F box/LRR repeat protein 1; F-box protein Skp2; F-box/LRR-repeat protein 1; FBL 1; FBL1; FBXL 1; FBXL1; FLB 1; FLB1; MGC1366; p45; p45skp2; S phase kinase associated protein 2 (p45); S phase kinase associated protein 2; S-phase kinase-associated protein 2; S-phase kinase-associated protein 2 E3 ubiquitin protein ligase; SKP 2; Skp2; SKP2_HUMAN] |
| Gene, Accession # | [SKP2], Gene ID: 6502, NCBI: NP_001230049.1, UniProt: Q13309 |
| Catalog # | MBS9600382 |
| Price | $240, $280 |
| Order / More Info | SKP2/p45 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Zhang Q, Miao S, Li C, Cui K, Ge Q, Chen Z; Journal: Am J Transl Res. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies