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Antigenic Specificity | Human IDE |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | Bat, Gibbon, dog, gorilla, horse, human. predicted reactivity: monkey, bovine, porcine, rabbit, chicken, Xenopus, zebrafish (at least 90% immunogen sequence identity) |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 0.5 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human IDE. This antibody is expected to recognize both reported isoforms (NP_004960.1 and NP_001159418.1). Insulin Degrading Enzyme (IDE) encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of IDE for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. |
Immunogen | Immunogen Description: Synthetic peptide C-QQYNFDRDNTE from an internal region of human IDE (NP_004960.1, NP_001159418.1). |
Other Names | [IDE (Internal) IHC-plus; IDE; Abeta-degrading protease; Insulinase; INSULYSIN; Insulin protease; Insulin-degrading enzyme; Human IDE], [IDE; IDE; INSULYSIN; Insulinase] |
Gene, Accession # | [IDE], Gene ID: 3416, NCBI: NP_004960.2, UniProt: P14735 |
Catalog # | MBS242756 |
Price | $530 |
Order / More Info | Human IDE Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |