Edit |   |
---|---|
Antigenic Specificity | p42 MAPK |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total p42 MAPK protein. Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylatin |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human p42 MAPK. |
Other Names | [EC 2.7.11.24; ERK-2; ERK2; ERT1; Extracellular signal-regulated kinase 2] |
Gene, Accession # | [p42 MAPK], Gene ID: 5594, NCBI: NP_002736.3, UniProt: P28482 |
Catalog # | MBS9401307 |
Price | $200, $255 |
Order / More Info | p42 MAPK Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |