CD34, Mouse Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-CD34, Mouse antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | CD34, Mouse |
| Clone | MEC14.7 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | F, Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunoprecipitation (IP), P, Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Product Description: The monoclonal antibody MEC14.7 recognizes mouse CD34, a single-pass type I membrane glycophosphoprotein present on small vessel endothelial cells and hematopoietic progenitor cells. The apparent molecular mass of CD34 is heterogeneous, depending on the glycosylation state in different cell types. In cultured endothelioma cell lysate, CD34 has a molecular weight of ~100 kDa, whereas in lung lysates it is ~80 kDa. 2 Isoforms of CD34 exist, both are expressed on the cell surface.CD34 is an adhesion molecule performing a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. CD34 acts as a scaffold for the attachment of lineage specific gl |
| Immunogen | Immunogen: Murine transformed EC t-end.1 |
| Other Names | [Hematopoietic progenitor cell antigen CD34], [CD34; CD34] |
| Gene, Accession # | [CD34], Gene ID: 947, NCBI: AAB25223.1 |
| Catalog # | MBS584261 |
| Price | $420 |
| Order / More Info | CD34, Mouse Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Garlanda, C et al; Characterization of MEC 14.7, a new monoclonal antibody recognizing mouse CD34, a useful reagent for identifying and characterizing blood vessels and hematopoietic precursors. Eur J Cell Biol 1997, 73: 368 2. Dong, Q et al; A general strategy for isolation of endothelial cells from murine tissues: Characterization of two endothelial cell lines from the murine lung and subcutaneous sponge implants. Arterioscler Thromb Vasc Biol 1997, 17: 1599 3. Solberg, H et al; A functional overlap of plasminogen and MMPs regulates vascularization during placental development. Development 2003, 130: 4439 4. Almholt, K et al; Metastasis of transgenic breast cancer in plasminogen activator inhibitor-1 gene-deficient mice. Oncogene 2003, 22: 4389 5. Sho, E et al; Hemodynamic regulation of CD34 cell localization and differentiation in experimental aneurysms. Arterioscler Thromb Vasc Biol 2004, 24: 1916 6. Suganuma, T et al; Functional expression of the angiotensin II type 1 receptor in human ovarian carcinoma cells and its blockade therapy resulting in suppression of tumor invasion, angiogenesis, and peritoneal dissemination. Clin Cancer Res 2005, 11: 2686 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies