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Antigenic Specificity | AFP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-AFP Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with AFP from other sources has not been determined. Alpha-fetoprotein (AFP) is a major plasma protein produced by the yolk sac and the liver during fetal development. In adults, AFP expression is often associated with hepatoma or teratoma. However, hereditary persistence of AFP may also be found in individuals with no obvious pathology. AFP is thought to be the fetal counterpart of serum albumin, and the AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. AFP is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. AFP levels in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. |
Immunogen | Anti-AFP antibody was prepared from whole rabbit serum produced by repeated immunizations with an internal 14 amino acid synthetic peptide of human AFP. |
Other Names | AFP Antibody, FETA, HPAFP, Alpha-fetoprotein, Alpha-1-fetoprotein |
Gene, Accession # | AFP, Gene ID: 174, NCBI: NP_001125, UniProt: P02771 |
Catalog # | 600-401-X80 |
Price | $475 |
Order / More Info | AFP Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |