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Antigenic Specificity | AGAP4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein A purified |
Size | 25 µL |
Concentration | 1.04 mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-AGAP4 antibody was purified from monospecific antiserum by protein A affinity purification and the His-tag was removed by cross adsorption. An immunoblot assay detects overexpressed recombinant AGAP4. This antibody is designed, produced, and validated as part of a collaboration between Rockland and the National Cancer Institute (NCI). The AGAPs are the largest subgroup of the ArfGAP family with 11 genes in humans. AGAP4 (also known as Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4) is a GTPase activating protein. It is overexpressed in cancer cells, prevents apoptosis and promotes cancer cell invasion. AGAP4 and other AGAP proteins likely function in the secretory pathway, which could explain a link with the invasive behavior of cancer cells. Reliable antibodies would be invaluable for studies of the physiologic function of the proteins and how is may be linked to cancer cell invasive behavior. Anti-AGAP4 Antibody is useful for researchers interested in Developmental Biology, apoptosis, Cancer, Immunology, and Nuclear Signaling research. |
Immunogen | Anti-AGAP4 antibody was prepared from whole rabbit serum produced by repeated immunizations with recombinant His-tagged AGAP4 protein. |
Other Names | rabbit anti-AGAP4 antibody, AGAP-4, AGAP 4, CTGLF1, MRIP2, Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4, Centaurin-gamma-like family member 1 |
Gene, Accession # | AGAP4, Gene ID: 119016, NCBI: NP_597703.2, UniProt: Q96P64 |
Catalog # | 200-401-P07S |
Price | $125 |
Order / More Info | AGAP4 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |