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Antigenic Specificity | AFAP1L |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-AFAP1L Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least four isoforms of AFAP1L1 are known to exist. This antibody is predicted to not cross-react with other AFAP family members. The actin filament-associated protein 1 (AFAP1)-like 1 protein is one of three members in the AFAP1 family of adaptor proteins. Like AFAP1, AFAP1L1 is an actin binding protein that has a role in actin cytoskeleton arrangement, but AFAP1L1 is thought to have a unique function distinct from AFAP1. AFAP1L1 colocalizes with cortactin and localizes to invadosomes, highly dynamic, actin-rich adhesion structures harboring metalloproteases, suggesting that AFAP1L1 affects invadosome formation (1, 4). Recent reports suggest that AFAP1L1 can be used as a prognostic marker for spindle cell sarcomas. |
Immunogen | Anti-AFAP1L1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid synthetic peptide near the N-terminus of human AFAP1L1. |
Other Names | AFAP1L Antibody, Actin filament-associated protein 1-like 1, AFAP1-like protein 1 |
Gene, Accession # | AFAP1L1, Gene ID: 134265, NCBI: NP_689619, UniProt: Q8TED9 |
Catalog # | 600-401-X78 |
Price | $475 |
Order / More Info | AFAP1L Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |