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Antigenic Specificity | AID |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-AID Antibody was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest cross-reactivity with AID with Human and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity with AID from other sources has not been determined. AID antibody detects human AID. Activation-induced cytidine deaminase (AID) was initially discovered as a homolog of the apolipoprotein B RNA-editing cytidine deaminase 1 (APOBEC1) that showed cytidine deaminase properties in stimulated B cell lines. It is necessary for somatic hypermutation and class switch recombination in B cells, but inappropriate or dysregulated expression AID is often found in tumors and B cell neoplasms. Although it is structurally and functionally similar to the APOBEC proteins, it appears unlikely that AID deaminates dC to dU residues in HIV cDNA as does APOBEC3G. Anti-AID antibodies are ideal for investigators involved in Apolipoprotein and Infectious Disease research. |
Immunogen | AID Antibody was produced from whole rabbit serum prepared by repeated immunizations with a peptide corresponding to amino acids near the c-terminus of human AID. |
Other Names | ARP2, CDA2, HIGM2, HEL-S-284, AID, Single-stranded DNA cytosine deaminase, Activation-induced cytidine deaminase |
Gene, Accession # | AID NCBI: AAM95402, UniProt: Q8NFC5 |
Catalog # | 600-401-G74 |
Price | $475 |
Order / More Info | AID Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |