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Antigenic Specificity | Adenosine Deaminase |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, bovine calf spleen |
Isotype | n/a |
Format | serum |
Size | 2 mL |
Concentration | 90 mg/mL |
Applications | ELISA, Immunoprecipitation, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This product was prepared from monospecific antiserum by a delipidation and defibrination. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-rabbit serum, purified and partially purified Adenosine Deaminase [Calf Spleen]. Cross reactivity against Adenosine Deaminase from other tissues and species may occur but have not been specifically determined. Adenosine Deaminase catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. It plays an important role in purine metabolism and in adenosine homeostasis. Adenosine Deaminase modulates signaling by extracellular adenosine, therefore contributes indirectly to cellular signaling events. It acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion. Adenosine Deaminase enhances dendritic cell immunogenicity by affecting dendritic cell costimulatory molecule expression and cytokines and chemokines secretion. It enhances CD4+ T-cell differentiation and proliferation. And acts as a positive modulator of adenosine receptors ADORA1 and ADORA2A, by enhancing their ligand affinity via conformational change. It stimulates plasminogen activation. It also plays a role in male fertility and a protective role in early post implantation embryonic development. |
Immunogen | Adenosine Deaminase [Calf Spleen] |
Other Names | rabbit anti-Adenosine Deaminase Antibody, Adenosine deaminase, Adenosine aminohydrolase |
Gene, Accession # | ADA, Gene ID: 280712, NCBI: NP_776312.1, UniProt: P56658 |
Catalog # | 100-401-140 |
Price | $1225 |
Order / More Info | Adenosine Deaminase Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |