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Product Name | CAY10734 |
Description | An S1P1 receptor agonist (IC50 = 0.6 nM); selectively binds S1P1 over S1P2, S1P3, and S1P4 receptors (IC50s = >10,000, 12,000, and 70 nM, respectively) but does also bind S1P5 receptors (IC50 = 1 nM) in radioligand binding assays; reduces the number of peripheral blood lymphocytes in mice, rats, and dogs, with the maximal response achieved at 10, 0.5, and 0.5 mg/kg, respectively; increases graft survival in a rat skin allograft model at 5 mg/kg per day in combination with CsA |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 868618-63-7 S1-P1 P2 P3 P4 P5 S1P-1 2 3 4 5 CAY-10734 |
Gene, Accession, CAS # | CAS: 635701-59-6 |
Catalog # | 10007833-5 |
Price | $139.00 |
Order / More Info | CAY10734 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |