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Product Name | TGR5 Receptor Agonist |
Description | An agonist of the bile acid G protein-coupled receptor TGR5 (EC50s = 31.6-158.5 nM in cell-based assays); stimulates cAMP formation in HEK293 cells expressing TGR5 (EC50 = 2.3 pM); increases GLP-1 secretion and decreases glucose levels in the hepatic portal vein in dogs at 1 mg/kg when administered in combination with glucose; inhibits the CYP isozymes CYP2C19 and CYP3A4 (IC50s = 316.2 and 1,259 nM, respectively) |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | TGR-5 CCDC HEK-293 GLP1 P-450 CYP-2C19 3A4 |
Gene, Accession, CAS # | CAS: 1197300-24-5 |
Catalog # | 16291-25 |
Price | $456.00 |
Order / More Info | TGR5 Receptor Agonist from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |