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Product Name | HLA-B*40:01 (EEAIVAYTL) Class I Tetramer, 500 Tests |
Description | This protocol is designed to evaluate the efficiency of peptide-HLA-I interaction and complex formation. The assay is based on detecting the β2-microglobulin (β2m) light chain subunit of recombinant HLA class I (HLA-I) complexes, where the heavy chain has been biotin tagged. These tagged complexes are subsequently captured by streptavidin coated beads, labelled with PE-conjugated anti-human β2m, and analyzed by flow cytometry. Since peptide-HLA-I complex formation is entirely peptide dependent, bead-associated signals will only be detected if the peptide in question supports the folding of the HLA-I allotype of interest; peptides that efficiently support folding will give strong signals whereas peptides that support folding sub-optimally, or not at all, will give moderate to non-detectable signals. |
Size | 500 tests |
Concentration | n/a |
Applications | RUO |
Other Names | kit, assay, EIA, enzyme immunoassay |
Gene, Accession, CAS # | n/a |
Catalog # | 1082-02-500 |
Price | $7555 |
Order / More Info | HLA-B*40:01 (EEAIVAYTL) Class I Tetramer, 500 Tests from EAGLE BIOSCIENCES INC. |
Product Specific References | n/a |