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Product Name | 17-AAG |
Description | Purity ≥98% by HPLC. Background: A semi-synthetic derivative of Geldanamycin that displays greater stability and lower in vivo toxicity compared to Geldanamycin. Binds to Heat shock protein 90 (Hsp90) (EC?? = 7.2 uM) in a manner similar to geldanamycin. Exhibits 100-fold higher affinity for tumor-derived Hsp90 over normal cells. Also inhibits Akt activation and HER2 expression in tumor cells. MW: 585.69 |
Size | 1 mg, 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | CAS: 75747-14-7 |
Catalog # | MBS842762 |
Price | $195, $550 |
Order / More Info | 17-AAG from MYBIOSOURCE INC. |
Product Specific References | n/a |