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Product Name | BIN1, 1-439aa, Human, His tag, E Coli |
Description | Purity > 90% by SDS-PAGE. BIN1, also known as SH3P9, is a nucleocytoplasmic adaptor protein, one of which was initially identified as MYC-interacting protein with features of a tumor suppressor. This protein interacts with and inhibits the oncogenic activity of the myc oncoprotein that has a major role in many human cancers. The loss of Bin1 may contribute to growth deregulation in cancer cells in carcinoma of the breast, colon, lung, cervix, prostate and liver. Recombinant human BIN1 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques. MW: 50.4 kDa (459aa) confirmed by MALDI-TOF |
Size | 0.1 mg, 0.5 mg |
Concentration | 1 mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | [Myc box-dependent-interacting protein 1; AMPH2; AMPHL; MGC10367; SH3P9; Amphiphysin II; Myc box-dependent-interacting protein 1], [BIN1; BIN1; CNM2; AMPH2; AMPHL; SH3P9; AMPHL] |
Gene, Accession, CAS # | [BIN1], Gene ID: 274, NCBI: AAH04101 |
Catalog # | MBS203671 |
Price | $310, $720 |
Order / More Info | BIN1, 1-439aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
Product Specific References | Sakamuro D., et al. (1996) Nat Genet. 14 (1):69-77. ; Nanda SK., et al. (2006) Gastroenterology. 130 (3):794-809.; |