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Product Name | Recombinant Rat UNC5H2/UNC5B protein |
Description | Domain: 27-373aa. Recombinant Rat UNC5B/UNC5B, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques. MW: 66.0kDa (590aa). Purity > 90% by SDS-PAGE. UNC5B/UNC5B, also known as Netrin receptor UNC5B, is one of four related receptors that comprise the UNC5 family and serve as receptors for the axon guidance molecule Netrin-1. Outside of the nervous system, UNC5B facilitates Netrin-1-mediated inhibition of capillary branching and leukocyte migration, as well as Netrin-1-mediated promotion of osteoclast differentiation. Also this protein activates DAPK1 which mediates apoptosis. It is believed to play a role in tumorgenesis. Additionally, It is thought to play a critical role in the development of atherosclerosis and the survival of renal tubular epithelial cells during acute kidney injury |
Size | 10ug, 20ug, 50ug, 100ug, 250ug, 500ug, 1mg |
Concentration | 0.25mg/ml (determined by Absorbance at 280nm) |
Applications | SDS-PAGE |
Other Names | unc-5 netrin receptor B, Unc5h2, unc-5 homolog 2, Protein unc-5 homolog B, netrin receptor UNC5B precursor, netrin receptor UNC5B, protein unc-5 homolog 2, unc5b |
Gene, Accession, CAS # | NCBI: NP_071543, UniProt: O08722 |
Catalog # | ATGP3950 |
Price | $150, $260, $350, $590, $1020, $1760, $2930 |
Order / More Info | Recombinant Rat UNC5H2/UNC5B protein from NKMAX Co. Ltd. |
Product Specific References | n/a |