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Product Name | Recombinant human RCAN3 protein |
Description | Domain: 56-241aa. Recombinant human RCAN3 protein, fused to His-tag at N-terminus, was expressed in E. coli. MW: 23.5 kDa (209aa). Purity > 90% by SDS-PAGE. Calcipressin-3, also known as RCAN3, is a 241 amino acid protein that potentially is involved in central nervous system development. RCAN3 inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Overexpression of calcipressin-3 results in inhibition of calcineurin activity towards the nuclear factor of activated T-cells (NFAT) transcription factors and also downregulates NFAT-dependent cytokine gene expression in activated Jurkat T-cells. Highest expression occurs in heart, skeletal muscle kidney, liver and peripheral blood leukocytes |
Size | 10ug, 50ug, 250ug |
Concentration | 0.5mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE,Denatured |
Other Names | Calcipressin-3, DSCR1L2, hRCN3, MCIP3, RCN3 |
Gene, Accession, CAS # | NCBI: NP_038469, UniProt: Q9UKA8 |
Catalog # | ATGP1811 |
Price | $80, $240, $720 |
Order / More Info | Recombinant human RCAN3 protein from NKMAX Co. Ltd. |
Product Specific References | n/a |