Edit |   |
---|---|
Product Name | Matrix Metalloproteinase-9 (MMP-9) |
Description | Purity >95% by SDS-PAGE. atrix metalloproteinases are a family of zinc and calcium dependent endopeptidases, which degrade extracellular matrix proteins. MMP-9 is secreted as a 92kDa zymogen. Cleavage of pro-MMP-9 results in the active enzyme with a molecular weight of ~82kDa. MMP-9 has a gelatin binding domain consisting of three fibronectin type II units, a catalytic domain containing the zinc-binding site, a proline-rich type V collagen-homologous domain and a hemopexin-like domain. MMP9 is produced by monocytes, macrophages, neutrophils, keratinocytes, fibroblasts, osteoclasts and endothelial cells, and is involved in inflammatory responses, tissue remodelling, wound healing, tumour growth and metastasis |
Size | 1mg |
Concentration | n/a |
Applications | RUO |
Other Names | Recombinant protein. Matrix metalloproteinase 9, gelatinase B, CLG4B, GELB |
Gene, Accession, CAS # | n/a |
Catalog # | RCP9311 |
Price | $2294 |
Order / More Info | Matrix Metalloproteinase-9 (MMP-9) from RANDOX LABORATORIES LTD. |
Product Specific References | Pourmotabbed, T et al., Biochim Biophys Acta. 1204 (1):97-107(1994). Romanic, AM. et al., Stroke 29 (5): 1020-1030 (1998). |