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Antigenic Specificity | WNT1 Inducible Signaling Pathway Protein 3 / WISP3 (CCN6) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | WISP3 is a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. WISP3 is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of the WISP3 gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis. |
Immunogen | KLH-conjugated synthetic peptide between 305-335 amino acids from the Central region of human WISP3. |
Other Names | WNT1-inducible-signaling pathway protein 3, WISP-3, CCN family member 6, WISP3, CCN6, UNQ462/PRO790/PRO956, WNT1-inducible-signaling pathway protein 3, WNT1-inducible-signaling pathway protein 3, WNT1-inducible-signaling pathway protein 3 , WNT1-inducible-signaling pathway protein 3 , WISP-3, WISP-3, WISP-3 , WISP-3 , CCN family member 6, CCN family member 6, CCN family member 6 , CCN family member 6 , WISP3, WISP3, WISP3 , WISP3 , CCN6, CCN6, CCN6 , CCN6 , UNQ462/PRO790/PRO956, UNQ462/PRO790/PRO956, UNQ462/PRO790/PRO956 , UNQ462/PRO790/PRO956 |
Gene, Accession # | UniProt: O95389 |
Catalog # | abx032755 |
Price | please inquire |
Order / More Info | WNT1 Inducible Signaling Pathway Protein 3 / WISP3 (CCN6) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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