FK506 Binding Protein 4 (FKBP4) Antibody from ABBEXA LTD

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Antigenic SpecificityFK506 Binding Protein 4 (FKBP4)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpurified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB, FCM
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DescriptionFKBP4 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506. It interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes. This protein is known to associate with phytanoyl-CoA alpha-hydroxylase. It can also associate with two heat shock proteins (hsp90 and hsp70) and thus may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors. This protein correlates strongly with adeno-associated virus type 2 vectors (AAV) resulting in a significant increase in AAV-mediated transgene expression in human cell lines. Thus this protein is thought to have important implications for the optimal use of AAV vectors in human gene therapy.
ImmunogenKLH-conjugated synthetic peptide between 186-216 amino acids from the Central region of human FKBP4.
Other NamesFKBP4, FKBP52, Peptidyl-prolyl cis-trans isomerase FKBP4, 51 kDa FK506-binding protein, 52 kDa FK506-binding protein, 59 kDa immunophilin, FK506-binding protein 4, FKBP59, HSP-binding immunophilin, Immunophilin FKBP52, Rotamase, N-terminally processed, PPIase FKBP4, FKBP51, 52 kDa FKBP, FKBP-52, p59, FKBP-4, HBI, p52, Hsp56, PPIase, FKBP4, FKBP4, FKBP4 , FKBP4 , FKBP52, FKBP52, FKBP52 , FKBP52 , Peptidyl-prolyl cis-trans isomerase FKBP4, Peptidyl-prolyl cis-trans isomerase FKBP4, Peptidyl-prolyl cis-trans isomerase FKBP4 , Peptidyl-prolyl cis-trans isomerase FKBP4 , 51 kDa FK506-binding protein, 51 kDa FK506-binding protein, 51 kDa FK506-binding protein , 51 kDa FK506-binding protein , 52 kDa FK506-binding protein, 52 kDa FK506-binding protein, 52 kDa FK506-binding protein , 52 kDa FK506-binding protein , 59 kDa immunophilin, 59 kDa immunophilin, 59 kDa immunophilin , 59 kDa immunophilin , FK506-binding protein 4, FK506-binding protein 4, FK506-binding protein 4 , FK506-binding
Gene, Accession #UniProt: Q02790
Catalog #abx033367
Priceplease inquire
Order / More InfoFK506 Binding Protein 4 (FKBP4) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
181 Cambridge Science Park
Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950

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