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Antigenic Specificity | Transmembrane Emp24 Domain-Containing Protein 6 (TMED6) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TMED6 (transmembrane emp24 domain-containing protein 6) is a 240 amino acid single-pass type I membrane protein that belongs to the EMP24/GP25L family and contains one GOLD domain. The gene that encodes TMED6 contains around 8, 564 bases and maps to human chromosome 16q22.1. Encoding over 900 genes and consisting of approximately 90 million base pairs, chromosome 16 makes up nearly 3% of the human genome and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, when mutated, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. Alterations in the CREB gene and NOD2 gene, both of which are located on chromosome 16, result in Rubinstein-Taybi syndrome and Crohn's disease, respectively. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. |
Immunogen | KLH-conjugated synthetic peptide between 125-153 amino acids from the Central region of human TMED6. |
Other Names | TMED6, P24gamma5, PRO34237, SPLL9146, P24 Family Protein Gamma-5, Transmembrane emp24 domain-containing protein 6, TMED6, TMED6, TMED6 , TMED6 , P24gamma5, P24gamma5, P24gamma5 , P24gamma5 , PRO34237, PRO34237, PRO34237 , PRO34237 , SPLL9146, SPLL9146, SPLL9146 , SPLL9146 , P24 Family Protein Gamma-5, P24 Family Protein Gamma-5, P24 Family Protein Gamma-5 , P24 Family Protein Gamma-5 , Transmembrane emp24 domain-containing protein 6, Transmembrane emp24 domain-containing protein 6, Transmembrane emp24 domain-containing protein 6 , Transmembrane emp24 domain-containing protein 6 |
Gene, Accession # | TMED6, UniProt: Q8WW62 |
Catalog # | abx028947 |
Price | please inquire |
Order / More Info | Transmembrane Emp24 Domain-Containing Protein 6 (TMED6) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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