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Antigenic Specificity | Cbp/P300-Interacting Transactivator 2 (CITED2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100 µg, |
Concentration | 2 mg/ml |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cbp/P300-Interacting Transactivator 2 (CITED2) antibody is a Rabbit polyclonal antibody for the detection of CITED2. Transcriptional coactivator of the p300/CBP-mediated transcription complex. Acts as a bridge, linking TFAP2 transcription factors and the p300/CBP transcriptional coactivator complex in order to stimulate TFAP2-mediated transcriptional activation. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Stimulates the peroxisome proliferator-activated receptors PPARA transcriptional activity. Enhances estrogen-dependent transactivation mediated by estrogen receptors. Acts also as a transcriptional corepressor; interferes with the binding of the transcription factors HIF1A or STAT2 and the p300/CBP transcriptional coactivator complex. Participates in sex determination and early gonad development by stimulating transcription activation of SRY. Plays a role in controlling left-right patterning during embryogenesis; potentiates transcriptional activation of NODAL-mediated gene transcription in the left lateral plate mesoderm (LPM). Plays an essential role in differentiation of the adrenal cortex from the adrenogonadal primordium (AGP) ; stimulates WT1-mediated transcription activation thereby up-regulating the nuclear hormone receptor NR5A1 promoter activity. Associates with chromatin to the PITX2 P1 promoter region. |
Immunogen | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
Other Names | CITED2, MRG 1, MRG1, MSG related protein 1, P35SRJ, CITED2, CITED2, CITED2 , CITED2 , MRG 1, MRG 1, MRG 1 , MRG 1 , MRG1, MRG1, MRG1 , MRG1 , MSG related protein 1, MSG related protein 1, MSG related protein 1 , MSG related protein 1 , P35SRJ, P35SRJ, P35SRJ , P35SRJ |
Gene, Accession # | CITED2, Gene ID: 10370, UniProt: Q99967 |
Catalog # | abx146762 |
Price | please inquire |
Order / More Info | Cbp/P300-Interacting Transactivator 2 (CITED2) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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