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Antigenic Specificity | Apoptosis Signal Regulating Kinase 1 (ASK1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This product is currently in development. The lead time for this product may be several months. Please contact us at info@abbexa.com for an updated lead time before purchasing this product. Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1, 374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK) /stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK. |
Immunogen | KLH-conjugated synthetic peptide between 61-90 amino acids from human ASK1 (MEKK5/MAP3K5). |
Other Names | Apoptosis signal- regulating kinase 1, ASK-1, kinase ASK1, M3K5, MAP3K5, MAPK/ERK kinase kinase 5, MAPKKK5, MEK kinase 5, MEKK 5, MEKK5, Mitogen-activated protein kinase kinase kinase 5, ASK1, Apoptosis signal-regulating kinase 1, MAP3-K5, Apoptosis signal- regulating kinase 1, Apoptosis signal- regulating kinase 1, Apoptosis signal- regulating kinase 1 , Apoptosis signal- regulating kinase 1 , ASK-1, ASK-1, ASK-1 , ASK-1 , kinase ASK1, kinase ASK1, kinase ASK1 , kinase ASK1 , M3K5, M3K5, M3K5 , M3K5 , MAP3K5, MAP3K5, MAP3K5 , MAP3K5 , MAPK/ERK kinase kinase 5, MAPK/ERK kinase kinase 5, MAPK/ERK kinase kinase 5 , MAPK/ERK kinase kinase 5 , MAPKKK5, MAPKKK5, MAPKKK5 , MAPKKK5 , MEK kinase 5, MEK kinase 5, MEK kinase 5 , MEK kinase 5 , MEKK 5, MEKK 5, MEKK 5 , MEKK 5 , MEKK5, MEKK5, MEKK5 , MEKK5 , Mitogen-activated protein kinase kinase kinase 5, Mitogen-activated protein kinase kinase kinase 5, Mitogen-activated protein kinase kinase kinase 5 , Mitogen-activated protein kina |
Gene, Accession # | MAP3K5, UniProt: Q99683 |
Catalog # | abx033757 |
Price | please inquire |
Order / More Info | Apoptosis Signal Regulating Kinase 1 (ASK1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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