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Antigenic Specificity | Myosin-9 (MYH9) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IHC, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MYH9 Antibody is a Rabbit Polyclonal antibody against MYH9. Nonmuscle myosin is an actin-based motor protein essential to cell motility, cell division, migration, adhesion, and polarity. The holoenzyme consists of two identical heavy chains and two sets of light chains. The light chains (MLCs) regulate myosin II activity and stability. The heavy chains (NMHCs) are encoded by three genes, MYH9, MYH10, and MYH14, which generate three different nonmuscle myosin II isoforms, IIa, IIb, and IIc, respectively (reviewed in 1). While all three isoforms perform the same enzymatic tasks, binding to and contracting actin filaments coupled to ATP hydrolysis, their cellular functions do not appear to be redundant and they have different subcellular distributions (2-5). The carboxy-terminal tail domain of myosin II is important in isoform-specific subcellular localization (6). Phosphorylation of myosin IIa at Ser1943 contributes to the regulation of breast cancer cell migration (7). |
Immunogen | Recombinant fusion protein of human MYH9. |
Other Names | MYH9, Myosin Heavy Chain 9, Cellular Myosin Heavy Chain, Type A, Non-Muscle Myosin Heavy Chain Iia, Nonmuscle Myosin Heavy Chain II-A, Non-Muscle Myosin Heavy Chain A, NMMHC-IIA, Myosin-9, Myosin, Heavy Polypeptide 9, Non-Muscle, Non-Muscle Myosin Heavy Polypeptide 9, Myosin Heavy Chain, Non-Muscle IIa, Myosin, Heavy Chain 9, Non-Muscle, Non-Muscle Myosin Heavy Chain 9, NMMHC II-A, NMHC-II-A, NMMHC-A, BDPLT6, MATINS, NMMHCA, DFNA17, EPSTS, FTNS, MHA, MYH9, MYH9, MYH9, MYH9, Myosin Heavy Chain 9, Myosin Heavy Chain 9, Myosin Heavy Chain 9, Myosin Heavy Chain 9, Cellular Myosin Heavy Chain, Type A, Cellular Myosin Heavy Chain, Type A, Cellular Myosin Heavy Chain, Type A, Cellular Myosin Heavy Chain, Type A, Non-Muscle Myosin Heavy Chain Iia, Non-Muscle Myosin Heavy Chain Iia, Non-Muscle Myosin Heavy Chain Iia, Non-Muscle Myosin Heavy Chain Iia, Nonmuscle Myosin Heavy Chain II-A, Nonmuscle Myosin Heavy Chain II-A, Nonmuscle Myosin Heavy Chain II-A, Nonmuscle Myosin Heavy Chain II-A, Non-Muscle Myosin Heavy Chain A, Non-Muscle Myosin Heavy Chain A, Non-Muscle Myosin Heavy Chain A, Non-Muscle Myosin Heavy Chain A, NMMHC-IIA, NMMHC-IIA, NMMHC-IIA, NMMHC-IIA, Myosin-9, Myosin-9, Myosin-9, Myosin-9, Myosin, Heavy Polypeptide 9, Non-Muscle, Myosin, Heavy Polypeptide 9, Non-Muscle, Myosin, Heavy Polypeptide 9, Non-Muscle, Myosin, Heavy Polypeptide 9, Non-Muscle, Non-Muscle Myosin Heavy Polypeptide 9, Non-Muscle Myosin Heavy Polypeptide 9, Non-Muscle Myosin Heavy Polypeptide 9, Non-Muscle Myosin Heavy Polypeptide 9, Myosin Heavy Chain, Non-Muscle IIa, Myosin Heavy Chain, Non-Muscle IIa, Myosin Heavy Chain, Non-Muscle IIa, Myosin Heavy Chain, Non-Muscle IIa, Myosin, Heavy Chain 9, Non-Muscle, Myosin, Heavy Chain 9, Non-Muscle, Myosin, Heavy Chain 9, Non-Muscle, Myosin, Heavy Chain 9, Non-Muscle, Non-Muscle Myosin Heavy Chain 9, Non-Muscle Myosin Heavy Chain 9, Non-Muscle Myosin Heavy Chain 9, Non-Muscle Myosin Heavy Chain 9, NMMHC II-A, NMMHC II-A, NMMHC II-A, NMMHC II-A, NMHC-II-A, NMHC-II-A, NMHC-II-A, NMHC-II-A, NMMHC-A, NMMHC-A, NMMHC-A, NMMHC-A, BDPLT6, BDPLT6, BDPLT6, BDPLT6, MATINS, MATINS, MATINS, MATINS, NMMHCA, NMMHCA, NMMHCA, NMMHCA, DFNA17, DFNA17, DFNA17, DFNA17, EPSTS, EPSTS, EPSTS, EPSTS, FTNS, FTNS, FTNS, FTNS, MHA, MHA, MHA, MHA |
Gene, Accession # | MYH9, Gene ID: 4627, NCBI Accession: NP_002464.1, NM_002473.5, UniProt: P35579 |
Catalog # | abx000580 |
Price | please inquire |
Order / More Info | Myosin-9 (MYH9) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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