Edit |   |
---|---|
Antigenic Specificity | Protein Kinase C Alpha Type (PRKCA) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC, IF/ICC, FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Protein kinase C (PKC) is a family of serine and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. PKC alpha is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca (2+) handling in myocytes. |
Immunogen | KLH-conjugated synthetic peptide between 299-329 amino acids from the C-terminal region of human PKC alpha. |
Other Names | kinase PKC-alpha, KPCA, PKC III, PKC-A, PKC-alpha, PKC-III, PRKACA, PRKCA, Protein kinase C, alpha type, PKC alpha, PKCA, Protein kinase C alpha type, kinase PKC-alpha, kinase PKC-alpha, kinase PKC-alpha , kinase PKC-alpha , KPCA, KPCA, KPCA , KPCA , PKC III, PKC III, PKC III , PKC III , PKC-A, PKC-A, PKC-A , PKC-A , PKC-alpha, PKC-alpha, PKC-alpha , PKC-alpha , PKC-III, PKC-III, PKC-III , PKC-III , PRKACA, PRKACA, PRKACA , PRKACA , PRKCA, PRKCA, PRKCA , PRKCA , Protein kinase C, Protein kinase C, Protein kinase C , Protein kinase C , alpha type, alpha type, alpha type , alpha type , PKC alpha, PKC alpha, PKC alpha , PKC alpha , PKCA, PKCA, PKCA , PKCA , Protein kinase C alpha type, Protein kinase C alpha type, Protein kinase C alpha type , Protein kinase C alpha type |
Gene, Accession # | NCBI: NP_002728.1, UniProt: P17252 |
Catalog # | abx033114 |
Price | please inquire |
Order / More Info | Protein Kinase C Alpha Type (PRKCA) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950