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Antigenic Specificity | EXOSC6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene product constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly (A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation. |
Immunogen | KLH-conjugated synthetic peptide between 12-38 amino acids from the N-terminal region of human EXOSC6. |
Other Names | EXOSC6, MTR3, Exosome complex component MTR3, Exosome component 6, mRNA transport regulator 3 homolog, p11, EXOSC6, EXOSC6, EXOSC6 , EXOSC6 , MTR3, MTR3, MTR3 , MTR3 , Exosome complex component MTR3, Exosome complex component MTR3, Exosome complex component MTR3 , Exosome complex component MTR3 , Exosome component 6, Exosome component 6, Exosome component 6 , Exosome component 6 , mRNA transport regulator 3 homolog, mRNA transport regulator 3 homolog, mRNA transport regulator 3 homolog , mRNA transport regulator 3 homolog , p11, p11, p11 , p11 |
Gene, Accession # | UniProt: Q5RKV6 |
Catalog # | abx030751 |
Price | please inquire |
Order / More Info | EXOSC6 Antibody from ABBEXA LTD |
Product Specific References | n/a |
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