Edit |   |
---|---|
Antigenic Specificity | Glutamate Decarboxylase 2 (GAD2) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 100 µg, |
Concentration | 1.0 mg/ml |
Applications | WB, IHC, IP, RIA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Glutamate Decarboxylase 2 (GAD2) antibody is a Mouse monoclonal antibody against Glutamate Decarboxylase 2 (GAD2). This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. |
Immunogen | n/a |
Other Names | GAD2, Glutamate Decarboxylase 2, Glutamate Decarboxylase 2 (Pancreatic Islets And Brain, 65kDa), Glutamate Decarboxylase 65 KDa Isoform, 65 KDa Glutamic Acid Decarboxylase, GAD-65, GAD65, Glutamate Decarboxylase 2 (Pancreatic Islets And Brain, 65kD), Glutamate Decarboxylase-2 (Pancreas), EC 4.1.1.15, GAD2, GAD2, GAD2 , GAD2 , Glutamate Decarboxylase 2, Glutamate Decarboxylase 2, Glutamate Decarboxylase 2 , Glutamate Decarboxylase 2 , Glutamate Decarboxylase 2 (Pancreatic Islets And Brain, 65kDa), Glutamate Decarboxylase 2 (Pancreatic Islets And Brain, 65kDa), Glutamate Decarboxylase 2 (Pancreatic Islets And Brain, 65kDa) , Glutamate Decarboxylase 2 (Pancreatic Islets And Brain, 65kDa) , Glutamate Decarboxylase 65 KDa Isoform, Glutamate Decarboxylase 65 KDa Isoform, Glutamate Decarboxylase 65 KDa Isoform , Glutamate Decarboxylase 65 KDa Isoform , 65 KDa Glutamic Acid Decarboxylase, 65 KDa Glutamic Acid Decarboxylase, 65 KDa Glutamic Acid Decarboxylase , 65 KDa Glutamic Acid Decarbo |
Gene, Accession # | GAD2, Gene ID: 2572, NCBI: NM_000818.2, NM_001134366.1, UniProt: Q05329 |
Catalog # | abx415097 |
Price | please inquire |
Order / More Info | Glutamate Decarboxylase 2 (GAD2) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950