Edit |   |
---|---|
Antigenic Specificity | Beta-Secretase 1 (BACE1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100 µg, |
Concentration | 2 mg/ml |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Beta-Secretase 1 (BACE1) antibody is a Rabbit polyclonal antibody for the detection of BACE1. Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. |
Immunogen | beta-site APP-cleaving enzyme 1 |
Other Names | BACE1, Beta-Secretase 1, Membrane-Associated Aspartic Protease 2, Beta-Site APP Cleaving Enzyme 1, Beta-Site APP-Cleaving Enzyme, Aspartyl Protease 2, Memapsin-2, Asp 2, ASP2, BACE, Beta-Site Amyloid Beta A4 Precursor Protein-Cleaving Enzyme, Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1, Transmembrane Aspartic Proteinase Asp2, Beta-Secretase 1 Precursor Variant 1, Beta-Site APP-Cleaving Enzyme 1, APP Beta-Secretase, EC 3.4.23, KIAA1149, HSPC104, BACE1, BACE1, BACE1, BACE1 , BACE1 , Beta-Secretase 1, Beta-Secretase 1, Beta-Secretase 1 , Beta-Secretase 1 , Membrane-Associated Aspartic Protease 2, Membrane-Associated Aspartic Protease 2, Membrane-Associated Aspartic Protease 2 , Membrane-Associated Aspartic Protease 2 , Beta-Site APP Cleaving Enzyme 1, Beta-Site APP Cleaving Enzyme 1, Beta-Site APP Cleaving Enzyme 1 , Beta-Site APP Cleaving Enzyme 1 , Beta-Site APP-Cleaving Enzyme, Beta-Site APP-Cleaving Enzyme, Beta-Site APP-Cleaving Enzyme , Beta-Site APP-Cleaving Enzyme , |
Gene, Accession # | BACE1, Gene ID: 23621, UniProt: P56817 |
Catalog # | abx148521 |
Price | please inquire |
Order / More Info | Beta-Secretase 1 (BACE1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950