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Antigenic Specificity | Serine/threonine-Protein Kinase TBK1 (Tbk1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Serine/threonine protein involved in the signaling cascade converging to the activation of the transcription factor NF-kappa-B. May function as an IKK kinase, playing an essential role in the transcription of a subset of a TNF-alpha-induced genes. Also mediates production of RANTES/CCL5 and interferon-beta/IFNB1. Has a pivotal role in the innate immune response. Phosphorylates and activates IRF3 and IRF7 and allows their nuclear localization. This leads to production of alpha/beta interferons and the development of a cellular antiviral state. It also seems to be a central factor in the induction of the antiviral interferon response. |
Immunogen | KLH-conjugated synthetic peptide between 8-35 amino acids from the N-terminal region of mouse Tbk1. |
Other Names | Tbk1, Serine/threonine-protein kinase TBK1, T2K, TANK-binding kinase 1, Tbk1, Tbk1, Tbk1 , Tbk1 , Serine/threonine-protein kinase TBK1, Serine/threonine-protein kinase TBK1, Serine/threonine-protein kinase TBK1 , Serine/threonine-protein kinase TBK1 , T2K, T2K, T2K , T2K , TANK-binding kinase 1, TANK-binding kinase 1, TANK-binding kinase 1 , TANK-binding kinase 1 |
Gene, Accession # | UniProt: Q9WUN2 |
Catalog # | abx029446 |
Price | please inquire |
Order / More Info | Serine/threonine-Protein Kinase TBK1 (Tbk1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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