Serine/threonine-Protein Kinase TBK1 (Tbk1) Antibody from ABBEXA LTD

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Antigenic SpecificitySerine/threonine-Protein Kinase TBK1 (Tbk1)
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse
Isotypen/a
Formatpeptide affinity purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB
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DescriptionSerine/threonine protein involved in the signaling cascade converging to the activation of the transcription factor NF-kappa-B. May function as an IKK kinase, playing an essential role in the transcription of a subset of a TNF-alpha-induced genes. Also mediates production of RANTES/CCL5 and interferon-beta/IFNB1. Has a pivotal role in the innate immune response. Phosphorylates and activates IRF3 and IRF7 and allows their nuclear localization. This leads to production of alpha/beta interferons and the development of a cellular antiviral state. It also seems to be a central factor in the induction of the antiviral interferon response.
ImmunogenKLH-conjugated synthetic peptide between 8-35 amino acids from the N-terminal region of mouse Tbk1.
Other NamesTbk1, Serine/threonine-protein kinase TBK1, T2K, TANK-binding kinase 1, Tbk1, Tbk1, Tbk1 , Tbk1 , Serine/threonine-protein kinase TBK1, Serine/threonine-protein kinase TBK1, Serine/threonine-protein kinase TBK1 , Serine/threonine-protein kinase TBK1 , T2K, T2K, T2K , T2K , TANK-binding kinase 1, TANK-binding kinase 1, TANK-binding kinase 1 , TANK-binding kinase 1
Gene, Accession #UniProt: Q9WUN2
Catalog #abx029446
Priceplease inquire
Order / More InfoSerine/threonine-Protein Kinase TBK1 (Tbk1) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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