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Antigenic Specificity | Cleaved-CASP3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, IHC, DB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CASP3 encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. |
Immunogen | KLH-conjugated synthetic peptide between 149-175 amino acids from human Cleaved. |
Other Names | CASP3, CPP32, Caspase-3, Apopain, Cysteine protease CPP32, Protein Yama, SREBP cleavage activity 1, Caspase-3 subunit p17, Caspase-3 subunit p12, CASP3, CASP3, CASP3 , CASP3 , CPP32, CPP32, CPP32 , CPP32 , Caspase-3, Caspase-3, Caspase-3 , Caspase-3 , Apopain, Apopain, Apopain , Apopain , Cysteine protease CPP32, Cysteine protease CPP32, Cysteine protease CPP32 , Cysteine protease CPP32 , Protein Yama, Protein Yama, Protein Yama , Protein Yama , SREBP cleavage activity 1, SREBP cleavage activity 1, SREBP cleavage activity 1 , SREBP cleavage activity 1 , Caspase-3 subunit p17, Caspase-3 subunit p17, Caspase-3 subunit p17 , Caspase-3 subunit p17 , Caspase-3 subunit p12, Caspase-3 subunit p12, Caspase-3 subunit p12 , Caspase-3 subunit p12 |
Gene, Accession # | UniProt: P42574 |
Catalog # | abx032087 |
Price | please inquire |
Order / More Info | Cleaved-CASP3 Antibody from ABBEXA LTD |
Product Specific References | n/a |
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