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Antigenic Specificity | Beta-Secretase 1 (BACE1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is bACE1. This protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. |
Immunogen | KLH-conjugated synthetic peptide between 476-501 amino acids from human BACE. |
Other Names | BACE1, Beta-Secretase 1, Membrane-Associated Aspartic Protease 2, Beta-Site APP Cleaving Enzyme 1, Beta-Site APP-Cleaving Enzyme, Aspartyl Protease 2, Memapsin-2, Asp 2, ASP2, BACE, Beta-Site Amyloid Beta A4 Precursor Protein-Cleaving Enzyme, Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1, Transmembrane Aspartic Proteinase Asp2, Beta-Secretase 1 Precursor Variant 1, Beta-Site APP-Cleaving Enzyme 1, APP Beta-Secretase, EC 3.4.23, KIAA1149, HSPC104, BACE1, BACE1, BACE1, BACE1 , BACE1 , Beta-Secretase 1, Beta-Secretase 1, Beta-Secretase 1 , Beta-Secretase 1 , Membrane-Associated Aspartic Protease 2, Membrane-Associated Aspartic Protease 2, Membrane-Associated Aspartic Protease 2 , Membrane-Associated Aspartic Protease 2 , Beta-Site APP Cleaving Enzyme 1, Beta-Site APP Cleaving Enzyme 1, Beta-Site APP Cleaving Enzyme 1 , Beta-Site APP Cleaving Enzyme 1 , Beta-Site APP-Cleaving Enzyme, Beta-Site APP-Cleaving Enzyme, Beta-Site APP-Cleaving Enzyme , Beta-Site APP-Cleaving Enzyme , |
Gene, Accession # | BACE1, Gene ID: 23621, UniProt: P56817, P56818 |
Catalog # | abx033673 |
Price | please inquire |
Order / More Info | Beta-Secretase 1 (BACE1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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