Edit |   |
---|---|
Antigenic Specificity | Mitogen-Activated Protein Kinase 1 Phospho-Thr185/Tyr187 and 3 Phospho-Thr202/Tyr204 (MAPK1 / MAPK3) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IHC, IF/ICC, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Erk1 (pT202/Y204) / Erk2 (pT185/Y187) antibody is a Rabbit polyclonal antibody against Erk1 (pT202/Y204) / Erk2 (pT185/Y187). The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. |
Immunogen | Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding T202/Y204 of human Erk1/2. |
Other Names | ERK1/2, ERK-1, ERK1, ERT2, Extracellular signal- regulated kinase 1, Insulin-stimulated MAP2 kinase, kinase ERK1, MAP kinase 1, MAPK 1, MAPK3, Microtubule- associated protein-2 kinase, Mitogen-activated protein kinase 3, MK03, MNK1, p44-ERK1, p44-MAPK, PRKM3, Extracellular signal-regulated kinase 1, Microtubule-associated protein 2 kinase, MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk, Mitogen-activated protein kinase 1, Extracellular signal-regulated kinase 2, ERK-2, MAP kinase isoform p42, p42-MAPK, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2, MAP kinase 3, MAPK 3, MAP kinase isoform p44, ERK1/2, ERK1/2, ERK1/2 , ERK1/2 , ERK-1, ERK-1, ERK-1 , ERK-1 , ERK1, ERK1, ERK1 , ERK1 , ERT2, ERT2, ERT2 , ERT2 , Extracellular signal- regulated kinase 1, Extracellular signal- regulated kinase 1, Extracellular signal- regulated kinase 1 , Extracellular signal- regulated kinase 1 , Insulin-stimulated MAP2 kinase, Insulin-stimulated MAP2 kinase, In |
Gene, Accession # | MAPK1, MAPK3, Gene ID: 5594/5595, UniProt: P28482, P27361 |
Catalog # | abx000517 |
Price | please inquire |
Order / More Info | Mitogen-Activated Protein Kinase 1 Phospho-Thr185/Tyr187 and 3 Phospho-Thr202/Tyr204 (MAPK1 / MAPK3) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950