Edit |   |
---|---|
Antigenic Specificity | Myc Proto-Oncogene Protein (MYC) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100 µg, |
Concentration | 2 mg/ml |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Myc Proto-Oncogene Protein (MYC) antibody is a Rabbit polyclonal antibody for the detection of c-MYC. MYC contains one basic helix-loop-helix (bHLH) domain. This protein is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. It seems to activate the transcription of growth-related genes. It binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. This antibody is a rabbit polyclonal antibody raised against recombinant protein of human MYC.The 50kDa band recognized by antibody is the native form of MYC, while the other bands, between 60-70kDa, are the phosphorylated form of MYC [PMID: 12189186] |
Immunogen | v-myc myelocytomatosis viral oncogene homolog(avian) |
Other Names | 48.8kd, MYC, avian myelocytomatosis viral oncogene homolog, BHLHE39, c-Myc, Class E basic helix-loop-helix protein 39, MRTL, Myc proto-oncogene protein, myc-related translation/localization regulatory factor, Proto-oncogene c-Myc, Transcription factor p64, v-myc avian myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene homolog, c Myc, Myc proto oncogene protein, MYC tag, Proto oncogene c Myc, CMYC, C-MYS, V-MYC, 48.8kd, 48.8kd, 48.8kd , 48.8kd , MYC, MYC, MYC , MYC , avian myelocytomatosis viral oncogene homolog, avian myelocytomatosis viral oncogene homolog, avian myelocytomatosis viral oncogene homolog , avian myelocytomatosis viral oncogene homolog , BHLHE39, BHLHE39, BHLHE39 , BHLHE39 , c-Myc, c-Myc, c-Myc , c-Myc , Class E basic helix-loop-helix protein 39, Class E basic helix-loop-helix protein 39, Class E basic helix-loop-helix protein 39 , Class E basic helix-loop-helix protein 39 , MRTL, MRTL, MRTL , MRTL , Myc proto-oncogene protein, Myc pro |
Gene, Accession # | MYC, Gene ID: 4609, UniProt: P01106 |
Catalog # | abx011213 |
Price | please inquire |
Order / More Info | Myc Proto-Oncogene Protein (MYC) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950