Integrin Alpha 5 (ITGA5) Antibody from ABBEXA LTD
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| Antigenic Specificity | Integrin Alpha 5 (ITGA5) |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a |
| Format | ascites |
| Size | 100 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC, FCM |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. Integrin alpha 5 is a heterodimer that associates noncovalently with CD29/integrin beta 1 subunit to form the alpha 5 beta 1 very late antigen (VLA-5) complex. VLA-5 is a fibronectin receptor that is expressed on thymocytes, T-cells, monocytes and platelets. It is also found on very early B-cells and activated B-cells. VLA-5-mediated binding to fibronectin sends a costimulatory signal to T-cells and enhances Fc gamma R- and complement receptor-mediated phago-cytosis. It is also involved in monocyte migration into extracellular tissues. |
| Immunogen | Purified recombinant fragment of human ITGA5 expressed in E. Coli. |
| Other Names | CD49e, FNRA, VLA5A, ITGA5 receptor subunit alpha Integrin alpha-F VLA-5 CD49e antigen, Integrin alpha-5, Fibronectin receptor subunit alpha, Integrin alpha-F, VLA-5, CD49e antigen, Integrin alpha-5 heavy chain, Integrin alpha-5 light chain, ITGA5, integrin, alpha 5 (fibronectin receptor, alpha polypeptide), CD49 antigen-like family member E, CD49e, CD49e, CD49e , CD49e , FNRA, FNRA, FNRA , FNRA , VLA5A, VLA5A, VLA5A , VLA5A , ITGA5 receptor subunit alpha Integrin alpha-F VLA-5 CD49e antigen, ITGA5 receptor subunit alpha Integrin alpha-F VLA-5 CD49e antigen, ITGA5 receptor subunit alpha Integrin alpha-F VLA-5 CD49e antigen , ITGA5 receptor subunit alpha Integrin alpha-F VLA-5 CD49e antigen , Integrin alpha-5, Integrin alpha-5, Integrin alpha-5 , Integrin alpha-5 , Fibronectin receptor subunit alpha, Fibronectin receptor subunit alpha, Fibronectin receptor subunit alpha , Fibronectin receptor subunit alpha , Integrin alpha-F, Integrin alpha-F, Integrin alpha-F , Integrin alpha-F , |
| Gene, Accession # | ITGA5, Gene ID: 3678, UniProt: P08648 |
| Catalog # | abx011678 |
| Price | please inquire |
| Order / More Info | Integrin Alpha 5 (ITGA5) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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