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Antigenic Specificity | Transcriptional Repressor CTCF (CTCF) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, monkey |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IHC, IF/ICC, IP, ChIP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CTCF antibody is a Rabbit polyclonal antibody against CTCF. This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human CTCF (NP_006556.1). |
Other Names | 11-zinc finger protein, CCCTC-binding factor, CTCFL paralog, CTCF, Transcriptional repressor CTCF, 11-zinc finger protein, 11-zinc finger protein, 11-zinc finger protein , 11-zinc finger protein , CCCTC-binding factor, CCCTC-binding factor, CCCTC-binding factor , CCCTC-binding factor , CTCFL paralog, CTCFL paralog, CTCFL paralog , CTCFL paralog , CTCF, CTCF, CTCF , CTCF , Transcriptional repressor CTCF, Transcriptional repressor CTCF, Transcriptional repressor CTCF , Transcriptional repressor CTCF |
Gene, Accession # | CTCF, Gene ID: 10664, UniProt: P49711 |
Catalog # | abx001047 |
Price | please inquire |
Order / More Info | Transcriptional Repressor CTCF (CTCF) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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