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Antigenic Specificity | Thioredoxin-Interacting Protein (TXNIP) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. |
Immunogen | KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TXNIP. |
Other Names | TXNIP, VDUP1, Thioredoxin-interacting protein, Thioredoxin-binding protein 2, Vitamin D3 up-regulated protein 1, HHCPA78, THIF, TXNIP, TXNIP, TXNIP , TXNIP , VDUP1, VDUP1, VDUP1 , VDUP1 , Thioredoxin-interacting protein, Thioredoxin-interacting protein, Thioredoxin-interacting protein , Thioredoxin-interacting protein , Thioredoxin-binding protein 2, Thioredoxin-binding protein 2, Thioredoxin-binding protein 2 , Thioredoxin-binding protein 2 , Vitamin D3 up-regulated protein 1, Vitamin D3 up-regulated protein 1, Vitamin D3 up-regulated protein 1 , Vitamin D3 up-regulated protein 1 , HHCPA78, HHCPA78, HHCPA78 , HHCPA78 , THIF, THIF, THIF , THIF |
Gene, Accession # | TXNIP, UniProt: Q9H3M7 |
Catalog # | abx031250 |
Price | please inquire |
Order / More Info | Thioredoxin-Interacting Protein (TXNIP) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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