Nicastrin (NCSTN) Antibody from ABBEXA LTD

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Antigenic SpecificityNicastrin (NCSTN)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size20 µl, 50 µl, 100 µl, 200 µl
Concentration> 0.5 mg/ml
ApplicationsWB, IF/ICC
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DescriptionNCSTN antibody is a Rabbit polyclonal antibody against NCSTN. This gene encodes a Type I transmembrane glycoprotein that is an integral component of the multimeric gamma-secretase complex. The encoded protein cleaves integral membrane proteins, including Notch receptors and beta-amyloid precursor protein, and may be a stabilizing cofactor required for gamma-secretase complex assembly. The cleavage of beta-amyloid precursor protein yields amyloid beta peptide, the main component of the neuritic plaque and the hallmark lesion in the brains of patients with Alzheimer's disease; however, the nature of the encoded protein's role in Alzheimer's disease is not known for certain. Alternatively spliced transcript variants have been described, but their full-length nature has not been determined.
ImmunogenRecombinant protein of human NCSTN.
Other NamesAPH2, RP11-517F10.1, NCSTN, KIAA0253, APH2, APH2, APH2 , APH2 , RP11-517F10.1, RP11-517F10.1, RP11-517F10.1 , RP11-517F10.1 , NCSTN, NCSTN, NCSTN , NCSTN , KIAA0253, KIAA0253, KIAA0253 , KIAA0253
Gene, Accession #NCSTN, Gene ID: 23385, UniProt: Q92542
Catalog #abx000564
Priceplease inquire
Order / More InfoNicastrin (NCSTN) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
181 Cambridge Science Park
Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950

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