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Antigenic Specificity | Caspase 3 (CASP3) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly (ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, 7 and 9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage. |
Immunogen | Purified His-tagged Human CASP3 protein |
Other Names | CASP3, CPP32, Caspase-3, Apopain, Cysteine protease CPP32, Protein Yama, SREBP cleavage activity 1, Caspase-3 subunit p17, Caspase-3 subunit p12, CPP32B, SCA-1, CASP3, CASP3, CASP3 , CASP3 , CPP32, CPP32, CPP32 , CPP32 , Caspase-3, Caspase-3, Caspase-3 , Caspase-3 , Apopain, Apopain, Apopain , Apopain , Cysteine protease CPP32, Cysteine protease CPP32, Cysteine protease CPP32 , Cysteine protease CPP32 , Protein Yama, Protein Yama, Protein Yama , Protein Yama , SREBP cleavage activity 1, SREBP cleavage activity 1, SREBP cleavage activity 1 , SREBP cleavage activity 1 , Caspase-3 subunit p17, Caspase-3 subunit p17, Caspase-3 subunit p17 , Caspase-3 subunit p17 , Caspase-3 subunit p12, Caspase-3 subunit p12, Caspase-3 subunit p12 , Caspase-3 subunit p12 , CPP32B, CPP32B, CPP32B , CPP32B , SCA-1, SCA-1, SCA-1 , SCA-1 |
Gene, Accession # | NCBI: NP_004337.2, NP_116786.1, UniProt: P42574 |
Catalog # | abx034999 |
Price | please inquire |
Order / More Info | Caspase 3 (CASP3) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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