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Antigenic Specificity | ATM (pS1981) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, IF/ICC, DB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ATM belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. ATM and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in the gene encoding ATM are associated with ataxia telangiectasia, an autosomal recessive disorder. |
Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1981 of human ATM. |
Other Names | Ataxia telangiectasia mutated homolog, Ataxia telangiectasia mutated, kinase ATM, AT1, ATA, ATC, ATD, ATE, ATDC, TEL1, TELO1, Serine-protein kinase ATM, A-T mutated, AT Mutated, Telomere Maintenance 1, ATM Serine/Threonine Kinase, Ataxia telangiectasia mutated homolog, Ataxia telangiectasia mutated homolog, Ataxia telangiectasia mutated homolog , Ataxia telangiectasia mutated homolog , Ataxia telangiectasia mutated, Ataxia telangiectasia mutated, Ataxia telangiectasia mutated , Ataxia telangiectasia mutated , kinase ATM, kinase ATM, kinase ATM , kinase ATM , AT1, AT1, AT1 , AT1 , ATA, ATA, ATA , ATA , ATC, ATC, ATC , ATC , ATD, ATD, ATD , ATD , ATE, ATE, ATE , ATE , ATDC, ATDC, ATDC , ATDC , TEL1, TEL1, TEL1 , TEL1 , TELO1, TELO1, TELO1 , TELO1 , Serine-protein kinase ATM, Serine-protein kinase ATM, Serine-protein kinase ATM , Serine-protein kinase ATM , A-T mutated, A-T mutated, A-T mutated , A-T mutated , AT Mutated, AT Mutated, AT Mutated , AT Mutated , Telomere Mainte |
Gene, Accession # | UniProt: Q13315 |
Catalog # | abx032012 |
Price | please inquire |
Order / More Info | ATM (pS1981) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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