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Antigenic Specificity | Kinase Insert Domain Receptor Phospho-Tyr1175 (KDR pY1175) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100 µg, |
Concentration | 2 mg/ml |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Kinase Insert Domain Receptor Phospho-Tyr1175 (KDR pY1175) antibody is a Rabbit polyclonal antibody for the detection of Phospho-VEGF Receptor 2-Y1175. KDR, also named as VEGFR-2, FLK1 and CD309, is a receptor for VEGF or VEGFC. KDR which belongs to the protein kinase superfamily, has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. KDR functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. Mutations of this gene are implicated in infantile capillary hemangiomas. |
Immunogen | A phospho specific peptide corresponding to residues surrounding Y1175 of human VEGF Receptor 2 |
Other Names | CD309, Fetal liver kinase 1, FLK 1, FLK1, KDR, Kinase insert domain receptor, VEGF Receptor 2, VEGFR, VEGFR 2, VEGFR2, CD309, CD309, CD309 , CD309 , Fetal liver kinase 1, Fetal liver kinase 1, Fetal liver kinase 1 , Fetal liver kinase 1 , FLK 1, FLK 1, FLK 1 , FLK 1 , FLK1, FLK1, FLK1 , FLK1 , KDR, KDR, KDR , KDR , Kinase insert domain receptor, Kinase insert domain receptor, Kinase insert domain receptor , Kinase insert domain receptor , VEGF Receptor 2, VEGF Receptor 2, VEGF Receptor 2 , VEGF Receptor 2 , VEGFR, VEGFR, VEGFR , VEGFR , VEGFR 2, VEGFR 2, VEGFR 2 , VEGFR 2 , VEGFR2, VEGFR2, VEGFR2 , VEGFR2 |
Gene, Accession # | KDR, Gene ID: 3791, UniProt: P35968 |
Catalog # | abx239853 |
Price | please inquire |
Order / More Info | Kinase Insert Domain Receptor Phospho-Tyr1175 (KDR pY1175) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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