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Antigenic Specificity | V-Type Proton ATPase Subunit B, Kidney Isoform (ATP6V1B1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found in the kidney. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness. [provided by RefSeq]. |
Immunogen | KLH-conjugated synthetic peptide between 472-501 amino acids from the C-terminal region of human ATP6V1B1. |
Other Names | ATP6V1B1, ATP6B1, VATB, VPP3, V-type proton ATPase subunit B, kidney isoform, Endomembrane proton pump 58 kDa subunit, Vacuolar proton pump subunit B 1, ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1, MGC32642, RTA1B, VMA2, Vacuolar ATP synthase subunit B, V-ATPase subunit B 1, ATP6V1B1, ATP6V1B1, ATP6V1B1 , ATP6V1B1 , ATP6B1, ATP6B1, ATP6B1 , ATP6B1 , VATB, VATB, VATB , VATB , VPP3, VPP3, VPP3 , VPP3 , V-type proton ATPase subunit B, V-type proton ATPase subunit B, V-type proton ATPase subunit B , V-type proton ATPase subunit B , kidney isoform, kidney isoform, kidney isoform , kidney isoform , Endomembrane proton pump 58 kDa subunit, Endomembrane proton pump 58 kDa subunit, Endomembrane proton pump 58 kDa subunit , Endomembrane proton pump 58 kDa subunit , Vacuolar proton pump subunit B 1, Vacuolar proton pump subunit B 1, Vacuolar proton pump subunit B 1 , Vacuolar proton pump subunit B 1 , ATPase, ATPase, ATPase , ATPase , H+ transporting, H+ transporting, H+ |
Gene, Accession # | UniProt: P15313 |
Catalog # | abx026703 |
Price | please inquire |
Order / More Info | V-Type Proton ATPase Subunit B, Kidney Isoform (ATP6V1B1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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