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Antigenic Specificity | DNA Damage-Binding Protein 2 (DDB2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DDB2 antibody is a Rabbit polyclonal antibody against DDB2. This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene. |
Immunogen | Recombinant protein of human DDB2. |
Other Names | damage-specific DNA binding protein 2, Damage-specific DNA-binding protein 2, DDB p48 subunit, Ddb2, DDBb, DNA damage-binding protein 2, UV-damaged DNA-binding protein 2, UV-DDB 2, Xeroderma pigmentosum group E protei, FLJ34321, UV-DDB2, Xeroderma Pigmentosum Group E Protein, damage-specific DNA binding protein 2, damage-specific DNA binding protein 2, damage-specific DNA binding protein 2 , damage-specific DNA binding protein 2 , Damage-specific DNA-binding protein 2, Damage-specific DNA-binding protein 2, Damage-specific DNA-binding protein 2 , Damage-specific DNA-binding protein 2 , DDB p48 subunit, DDB p48 subunit, DDB p48 subunit , DDB p48 subunit , Ddb2, Ddb2, Ddb2 , Ddb2 , DDBb, DDBb, DDBb , DDBb , DNA damage-binding protein 2, DNA damage-binding protein 2, DNA damage-binding protein 2 , DNA damage-binding protein 2 , UV-damaged DNA-binding protein 2, UV-damaged DNA-binding protein 2, UV-damaged DNA-binding protein 2 , UV-damaged DNA-binding protein 2 , UV-DDB 2, UV-DDB |
Gene, Accession # | DDB2, Gene ID: 1643, UniProt: Q92466 |
Catalog # | abx001528 |
Price | please inquire |
Order / More Info | DNA Damage-Binding Protein 2 (DDB2) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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