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Antigenic Specificity | MYC (pT358) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 50 µl, 100 µl, 200 µl, |
Concentration | > 0.5 mg/ml |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MYC (pT358) antibody is a Rabbit polyclonal antibody against MYC (pT358). The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. |
Immunogen | Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding T358 of human MYC. |
Other Names | 48.8kd, MYC, avian myelocytomatosis viral oncogene homolog, BHLHE39, c-Myc, Class E basic helix-loop-helix protein 39, MRTL, Myc proto-oncogene protein, myc-related translation/localization regulatory factor, Proto-oncogene c-Myc, Transcription factor p64, v-myc avian myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene homolog, c Myc, Myc proto oncogene protein, MYC tag, Proto oncogene c Myc, CMYC, C-MYS, V-MYC, 48.8kd, 48.8kd, 48.8kd , 48.8kd , MYC, MYC, MYC , MYC , avian myelocytomatosis viral oncogene homolog, avian myelocytomatosis viral oncogene homolog, avian myelocytomatosis viral oncogene homolog , avian myelocytomatosis viral oncogene homolog , BHLHE39, BHLHE39, BHLHE39 , BHLHE39 , c-Myc, c-Myc, c-Myc , c-Myc , Class E basic helix-loop-helix protein 39, Class E basic helix-loop-helix protein 39, Class E basic helix-loop-helix protein 39 , Class E basic helix-loop-helix protein 39 , MRTL, MRTL, MRTL , MRTL , Myc proto-oncogene protein, Myc pro |
Gene, Accession # | MYC, Gene ID: 4609, UniProt: P01106 |
Catalog # | abx000458 |
Price | please inquire |
Order / More Info | MYC (pT358) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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