GRIA2 (pS880) Antibody from ABBEXA LTD
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| Antigenic Specificity | GRIA2 (pS880) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 50 µl, 100 µl, 200 µl, |
| Concentration | > 0.5 mg/ml |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | GRIA2 (pS880) antibody is a Rabbit polyclonal antibody against GRIA2 (pS880). Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Human and animal studies suggest that pre-mRNA editing is essential for brain function, and defective GRIA2 RNA editing at the Q/R site may be relevant to amyotrophic lateral sclerosis (ALS) etiology. Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene. |
| Immunogen | Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding S880 of human GRIA2. |
| Other Names | GluA2, GluR2, gluR-B, GluR-K2, GLURB, HBGR2, GluA2, GluA2, GluA2 , GluA2 , GluR2, GluR2, GluR2 , GluR2 , gluR-B, gluR-B, gluR-B , gluR-B , GluR-K2, GluR-K2, GluR-K2 , GluR-K2 , GLURB, GLURB, GLURB , GLURB , HBGR2, HBGR2, HBGR2 , HBGR2 |
| Gene, Accession # | GRIA2, Gene ID: 2891, UniProt: P42262 |
| Catalog # | abx000308 |
| Price | please inquire |
| Order / More Info | GRIA2 (pS880) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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